Role of hypoxia in cancer therapy by regulating the tumor microenvironment
Identifieur interne : 000454 ( Main/Exploration ); précédent : 000453; suivant : 000455Role of hypoxia in cancer therapy by regulating the tumor microenvironment
Auteurs : Xinming Jing [République populaire de Chine] ; Fengming Yang [République populaire de Chine] ; Chuchu Shao [République populaire de Chine] ; Ke Wei [République populaire de Chine] ; Mengyan Xie [République populaire de Chine] ; Hua Shen [République populaire de Chine] ; Yongqian Shu [République populaire de Chine]Source :
- Molecular Cancer [ 1476-4598 ] ; 2019.
Abstract
Clinical resistance is a complex phenomenon in major human cancers involving multifactorial mechanisms, and hypoxia is one of the key components that affect the cellular expression program and lead to therapy resistance. The present study aimed to summarize the role of hypoxia in cancer therapy by regulating the tumor microenvironment (TME) and to highlight the potential of hypoxia-targeted therapy.
Relevant published studies were retrieved from PubMed, Web of Science, and Embase using keywords such as hypoxia, cancer therapy, resistance, TME, cancer, apoptosis, DNA damage, autophagy, p53, and other similar terms.
Recent studies have shown that hypoxia is associated with poor prognosis in patients by regulating the TME. It confers resistance to conventional therapies through a number of signaling pathways in apoptosis, autophagy, DNA damage, mitochondrial activity, p53, and drug efflux.
Hypoxia targeting might be relevant to overcome hypoxia-associated resistance in cancer treatment.
Url:
DOI: 10.1186/s12943-019-1089-9
PubMed: 31711497
PubMed Central: 6844052
Affiliations:
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University,</institution></institution-wrap>Nanjing, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Nanjing</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1799 0784</institution-id><institution-id institution-id-type="GRID">grid.412676.0</institution-id><institution>Department of Oncology,</institution><institution>The First Affiliated Hospital of Nanjing Medical University,</institution></institution-wrap>Nanjing, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Nanjing</wicri:regionArea></affiliation></author><author><name sortKey="Shen, Hua" sort="Shen, Hua" uniqKey="Shen H" first="Hua" last="Shen">Hua Shen</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0000 9255 8984</institution-id><institution-id institution-id-type="GRID">grid.89957.3a</institution-id><institution>Department of Oncology,</institution><institution>The Affiliated Sir Run Run Hospital of Nanjing Medical University,</institution></institution-wrap>Nanjing, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Nanjing</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1799 0784</institution-id><institution-id institution-id-type="GRID">grid.412676.0</institution-id><institution>Department of Oncology,</institution><institution>The First Affiliated Hospital of Nanjing Medical University,</institution></institution-wrap>Nanjing, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Nanjing</wicri:regionArea></affiliation></author><author><name sortKey="Shu, Yongqian" sort="Shu, Yongqian" uniqKey="Shu Y" first="Yongqian" last="Shu">Yongqian Shu</name><affiliation wicri:level="1"><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0000 9255 8984</institution-id><institution-id institution-id-type="GRID">grid.89957.3a</institution-id><institution>Department of Oncology,</institution><institution>The Affiliated Sir Run Run Hospital of Nanjing Medical University,</institution></institution-wrap>Nanjing, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Nanjing</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 1799 0784</institution-id><institution-id institution-id-type="GRID">grid.412676.0</institution-id><institution>Department of Oncology,</institution><institution>The First Affiliated Hospital of Nanjing Medical University,</institution></institution-wrap>Nanjing, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Nanjing</wicri:regionArea></affiliation></author></analytic><series><title level="j">Molecular Cancer</title><idno type="eISSN">1476-4598</idno><imprint><date when="2019">2019</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Aim</title><p id="Par1">Clinical resistance is a complex phenomenon in major human cancers involving multifactorial mechanisms, and hypoxia is one of the key components that affect the cellular expression program and lead to therapy resistance. The present study aimed to summarize the role of hypoxia in cancer therapy by regulating the tumor microenvironment (TME) and to highlight the potential of hypoxia-targeted therapy.</p></sec><sec><title>Methods</title><p id="Par2">Relevant published studies were retrieved from PubMed, Web of Science, and Embase using keywords such as hypoxia, cancer therapy, resistance, TME, cancer, apoptosis, DNA damage, autophagy, p53, and other similar terms.</p></sec><sec><title>Results</title><p id="Par3">Recent studies have shown that hypoxia is associated with poor prognosis in patients by regulating the TME. It confers resistance to conventional therapies through a number of signaling pathways in apoptosis, autophagy, DNA damage, mitochondrial activity, p53, and drug efflux.</p></sec><sec><title>Conclusion</title><p id="Par4">Hypoxia targeting might be relevant to overcome hypoxia-associated resistance in cancer treatment.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Chen, W" uniqKey="Chen W">W Chen</name></author><author><name sortKey="Zheng, R" uniqKey="Zheng R">R Zheng</name></author><author><name sortKey="Baade, Pd" uniqKey="Baade P">PD Baade</name></author><author><name sortKey="Zhang, S" uniqKey="Zhang S">S Zhang</name></author><author><name sortKey="Zeng, H" uniqKey="Zeng H">H Zeng</name></author><author><name sortKey="Bray, F" uniqKey="Bray F">F Bray</name></author><author><name sortKey="Jemal, A" uniqKey="Jemal A">A Jemal</name></author><author><name sortKey="Yu, Xq" uniqKey="Yu X">XQ Yu</name></author><author><name sortKey="He, J" uniqKey="He J">J He</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gatti, L" uniqKey="Gatti L">L Gatti</name></author><author><name sortKey="Zunino, F" uniqKey="Zunino F">F Zunino</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gottesman, Mm" uniqKey="Gottesman M">MM Gottesman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sun, Y" uniqKey="Sun Y">Y Sun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, F" uniqKey="Chen F">F Chen</name></author><author><name sortKey="Zhuang, X" uniqKey="Zhuang X">X Zhuang</name></author><author><name sortKey="Lin, L" uniqKey="Lin L">L Lin</name></author><author><name sortKey="Yu, P" uniqKey="Yu P">P Yu</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Shi, Y" uniqKey="Shi Y">Y Shi</name></author><author><name sortKey="Hu, G" uniqKey="Hu G">G Hu</name></author><author><name sortKey="Sun, Y" uniqKey="Sun Y">Y Sun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, T" uniqKey="Wu T">T Wu</name></author><author><name sortKey="Dai, Y" uniqKey="Dai Y">Y Dai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shao, C" uniqKey="Shao C">C Shao</name></author><author><name sortKey="Yang, F" uniqKey="Yang F">F Yang</name></author><author><name sortKey="Miao, S" uniqKey="Miao S">S Miao</name></author><author><name sortKey="Liu, W" uniqKey="Liu W">W Liu</name></author><author><name sortKey="Wang, C" uniqKey="Wang C">C Wang</name></author><author><name sortKey="Shu, Y" uniqKey="Shu Y">Y Shu</name></author><author><name sortKey="Shen, H" uniqKey="Shen H">H Shen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brown, Jm" uniqKey="Brown J">JM Brown</name></author><author><name sortKey="Giaccia, Aj" uniqKey="Giaccia A">AJ Giaccia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Harris, Al" uniqKey="Harris A">AL Harris</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Koukourakis, Mi" uniqKey="Koukourakis M">MI Koukourakis</name></author><author><name sortKey="Giatromanolaki, A" uniqKey="Giatromanolaki A">A Giatromanolaki</name></author><author><name sortKey="Skarlatos, J" uniqKey="Skarlatos J">J Skarlatos</name></author><author><name sortKey="Corti, L" uniqKey="Corti L">L Corti</name></author><author><name sortKey="Blandamura, S" uniqKey="Blandamura S">S Blandamura</name></author><author><name sortKey="Piazza, M" uniqKey="Piazza M">M Piazza</name></author><author><name sortKey="Gatter, Kc" uniqKey="Gatter K">KC Gatter</name></author><author><name sortKey="Harris, Al" uniqKey="Harris A">AL Harris</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wigerup, C" uniqKey="Wigerup C">C Wigerup</name></author><author><name sortKey="Pahlman, S" uniqKey="Pahlman S">S Pahlman</name></author><author><name sortKey="Bexell, D" uniqKey="Bexell D">D Bexell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wilson, Wr" uniqKey="Wilson W">WR Wilson</name></author><author><name sortKey="Hay, Mp" uniqKey="Hay M">MP Hay</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Loges, S" uniqKey="Loges S">S Loges</name></author><author><name sortKey="Mazzone, M" uniqKey="Mazzone M">M Mazzone</name></author><author><name sortKey="Hohensinner, P" uniqKey="Hohensinner P">P Hohensinner</name></author><author><name sortKey="Carmeliet, P" uniqKey="Carmeliet P">P Carmeliet</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Minchinton, Ai" uniqKey="Minchinton A">AI Minchinton</name></author><author><name sortKey="Tannock, If" uniqKey="Tannock I">IF Tannock</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roma Rodrigues, Catarina" uniqKey="Roma Rodrigues C">Catarina Roma-Rodrigues</name></author><author><name sortKey="Mendes, Rita" uniqKey="Mendes R">Rita Mendes</name></author><author><name sortKey="Baptista, Pedro" uniqKey="Baptista P">Pedro Baptista</name></author><author><name sortKey="Fernandes, Alexandra" uniqKey="Fernandes A">Alexandra Fernandes</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Birner, P" uniqKey="Birner P">P Birner</name></author><author><name sortKey="Schindl, M" uniqKey="Schindl M">M Schindl</name></author><author><name sortKey="Obermair, A" uniqKey="Obermair A">A Obermair</name></author><author><name sortKey="Plank, C" uniqKey="Plank C">C Plank</name></author><author><name sortKey="Breitenecker, G" uniqKey="Breitenecker G">G Breitenecker</name></author><author><name sortKey="Oberhuber, G" uniqKey="Oberhuber G">G Oberhuber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, Y" uniqKey="Huang Y">Y Huang</name></author><author><name sortKey="Lin, D" uniqKey="Lin D">D Lin</name></author><author><name sortKey="Taniguchi, Cm" uniqKey="Taniguchi C">CM Taniguchi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mckeown, Sr" uniqKey="Mckeown S">SR McKeown</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Semenza, Gl" uniqKey="Semenza G">GL Semenza</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wiesener, Ms" uniqKey="Wiesener M">MS Wiesener</name></author><author><name sortKey="Jurgensen, Js" uniqKey="Jurgensen J">JS Jurgensen</name></author><author><name sortKey="Rosenberger, C" uniqKey="Rosenberger C">C Rosenberger</name></author><author><name sortKey="Scholze, Ck" uniqKey="Scholze C">CK Scholze</name></author><author><name sortKey="Horstrup, Jh" uniqKey="Horstrup J">JH Horstrup</name></author><author><name sortKey="Warnecke, C" uniqKey="Warnecke C">C Warnecke</name></author><author><name sortKey="Mandriota, S" uniqKey="Mandriota S">S Mandriota</name></author><author><name sortKey="Bechmann, I" uniqKey="Bechmann I">I Bechmann</name></author><author><name sortKey="Frei, Ua" uniqKey="Frei U">UA Frei</name></author><author><name sortKey="Pugh, Cw" uniqKey="Pugh C">CW Pugh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Semenza, Gl" uniqKey="Semenza G">GL Semenza</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Majmundar, Aj" uniqKey="Majmundar A">AJ Majmundar</name></author><author><name sortKey="Wong, Wj" uniqKey="Wong W">WJ Wong</name></author><author><name sortKey="Simon, Mc" uniqKey="Simon M">MC Simon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Semenza, Gl" uniqKey="Semenza G">GL Semenza</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nardinocchi, L" uniqKey="Nardinocchi L">L Nardinocchi</name></author><author><name sortKey="Puca, R" uniqKey="Puca R">R Puca</name></author><author><name sortKey="Sacchi, A" uniqKey="Sacchi A">A Sacchi</name></author><author><name sortKey="D Orazi, G" uniqKey="D Orazi G">G D'Orazi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sullivan, R" uniqKey="Sullivan R">R Sullivan</name></author><author><name sortKey="Pare, Gc" uniqKey="Pare G">GC Pare</name></author><author><name sortKey="Frederiksen, Lj" uniqKey="Frederiksen L">LJ Frederiksen</name></author><author><name sortKey="Semenza, Gl" uniqKey="Semenza G">GL Semenza</name></author><author><name sortKey="Graham, Ch" uniqKey="Graham C">CH Graham</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="He, J" uniqKey="He J">J He</name></author><author><name sortKey="Pei, L" uniqKey="Pei L">L Pei</name></author><author><name sortKey="Jiang, H" uniqKey="Jiang H">H Jiang</name></author><author><name sortKey="Yang, W" uniqKey="Yang W">W Yang</name></author><author><name sortKey="Chen, J" uniqKey="Chen J">J Chen</name></author><author><name sortKey="Liang, H" uniqKey="Liang H">H Liang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xia, S" uniqKey="Xia S">S Xia</name></author><author><name sortKey="Yu, S" uniqKey="Yu S">S Yu</name></author><author><name sortKey="Yuan, X" uniqKey="Yuan X">X Yuan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zunino, F" uniqKey="Zunino F">F Zunino</name></author><author><name sortKey="Perego, P" uniqKey="Perego P">P Perego</name></author><author><name sortKey="Pilotti, S" uniqKey="Pilotti S">S Pilotti</name></author><author><name sortKey="Pratesi, G" uniqKey="Pratesi G">G Pratesi</name></author><author><name sortKey="Supino, R" uniqKey="Supino R">R Supino</name></author><author><name sortKey="Arcamone, F" uniqKey="Arcamone F">F Arcamone</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Loo, G" uniqKey="Van Loo G">G van Loo</name></author><author><name sortKey="Saelens, X" uniqKey="Saelens X">X Saelens</name></author><author><name sortKey="Van Gurp, M" uniqKey="Van Gurp M">M van Gurp</name></author><author><name sortKey="Macfarlane, M" uniqKey="Macfarlane M">M MacFarlane</name></author><author><name sortKey="Martin, Sj" uniqKey="Martin S">SJ Martin</name></author><author><name sortKey="Vandenabeele, P" uniqKey="Vandenabeele P">P Vandenabeele</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Greijer, Ae" uniqKey="Greijer A">AE Greijer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sendoel, A" uniqKey="Sendoel A">A Sendoel</name></author><author><name sortKey="Kohler, I" uniqKey="Kohler I">I Kohler</name></author><author><name sortKey="Fellmann, C" uniqKey="Fellmann C">C Fellmann</name></author><author><name sortKey="Lowe, Sw" uniqKey="Lowe S">SW Lowe</name></author><author><name sortKey="Hengartner, Mo" uniqKey="Hengartner M">MO Hengartner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rouschop, Km" uniqKey="Rouschop K">KM Rouschop</name></author><author><name sortKey="Van Den Beucken, T" uniqKey="Van Den Beucken T">T van den Beucken</name></author><author><name sortKey="Dubois, L" uniqKey="Dubois L">L Dubois</name></author><author><name sortKey="Niessen, H" uniqKey="Niessen H">H Niessen</name></author><author><name sortKey="Bussink, J" uniqKey="Bussink J">J Bussink</name></author><author><name sortKey="Savelkouls, K" uniqKey="Savelkouls K">K Savelkouls</name></author><author><name sortKey="Keulers, T" uniqKey="Keulers T">T Keulers</name></author><author><name sortKey="Mujcic, H" uniqKey="Mujcic H">H Mujcic</name></author><author><name sortKey="Landuyt, W" uniqKey="Landuyt W">W Landuyt</name></author><author><name sortKey="Voncken, Jw" uniqKey="Voncken J">JW Voncken</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hu, T" uniqKey="Hu T">T Hu</name></author><author><name sortKey="Wang, L" uniqKey="Wang L">L Wang</name></author><author><name sortKey="Zhang, L" uniqKey="Zhang L">L Zhang</name></author><author><name sortKey="Lu, L" uniqKey="Lu L">L Lu</name></author><author><name sortKey="Shen, J" uniqKey="Shen J">J Shen</name></author><author><name sortKey="Chan, Rly" uniqKey="Chan R">RLY Chan</name></author><author><name sortKey="Li, M" uniqKey="Li M">M Li</name></author><author><name sortKey="Wu, Wkk" uniqKey="Wu W">WKK Wu</name></author><author><name sortKey="To, Kkw" uniqKey="To K">KKW To</name></author><author><name sortKey="Cho, Ch" uniqKey="Cho C">CH Cho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yan, Y" uniqKey="Yan Y">Y Yan</name></author><author><name sortKey="Xu, Z" uniqKey="Xu Z">Z Xu</name></author><author><name sortKey="Dai, S" uniqKey="Dai S">S Dai</name></author><author><name sortKey="Qian, L" uniqKey="Qian L">L Qian</name></author><author><name sortKey="Sun, L" uniqKey="Sun L">L Sun</name></author><author><name sortKey="Gong, Z" uniqKey="Gong Z">Z Gong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Flamant, L" uniqKey="Flamant L">L Flamant</name></author><author><name sortKey="Roegiers, E" uniqKey="Roegiers E">E Roegiers</name></author><author><name sortKey="Pierre, M" uniqKey="Pierre M">M Pierre</name></author><author><name sortKey="Hayez, A" uniqKey="Hayez A">A Hayez</name></author><author><name sortKey="Sterpin, C" uniqKey="Sterpin C">C Sterpin</name></author><author><name sortKey="De Backer, O" uniqKey="De Backer O">O De Backer</name></author><author><name sortKey="Arnould, T" uniqKey="Arnould T">T Arnould</name></author><author><name sortKey="Poumay, Y" uniqKey="Poumay Y">Y Poumay</name></author><author><name sortKey="Michiels, C" uniqKey="Michiels C">C Michiels</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Madan, E" uniqKey="Madan E">E Madan</name></author><author><name sortKey="Gogna, R" uniqKey="Gogna R">R Gogna</name></author><author><name sortKey="Pati, U" uniqKey="Pati U">U Pati</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, F" uniqKey="Li F">F Li</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y Wang</name></author><author><name sortKey="Zeller, Ki" uniqKey="Zeller K">KI Zeller</name></author><author><name sortKey="Potter, Jj" uniqKey="Potter J">JJ Potter</name></author><author><name sortKey="Wonsey, Dr" uniqKey="Wonsey D">DR Wonsey</name></author><author><name sortKey="O Donnell, Ka" uniqKey="O Donnell K">KA O'Donnell</name></author><author><name sortKey="Kim, J" uniqKey="Kim J">J Kim</name></author><author><name sortKey="Yustein, Jt" uniqKey="Yustein J">JT Yustein</name></author><author><name sortKey="Lee, La" uniqKey="Lee L">LA Lee</name></author><author><name sortKey="Dang, Cv" uniqKey="Dang C">CV Dang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sasabe, E" uniqKey="Sasabe E">E Sasabe</name></author><author><name sortKey="Tatemoto, Y" uniqKey="Tatemoto Y">Y Tatemoto</name></author><author><name sortKey="Li, D" uniqKey="Li D">D Li</name></author><author><name sortKey="Yamamoto, T" uniqKey="Yamamoto T">T Yamamoto</name></author><author><name sortKey="Osaki, T" uniqKey="Osaki T">T Osaki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fulda, S" uniqKey="Fulda S">S Fulda</name></author><author><name sortKey="Galluzzi, L" uniqKey="Galluzzi L">L Galluzzi</name></author><author><name sortKey="Kroemer, G" uniqKey="Kroemer G">G Kroemer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Deschoemaeker, S" uniqKey="Deschoemaeker S">S Deschoemaeker</name></author><author><name sortKey="Di Conza, G" uniqKey="Di Conza G">G Di Conza</name></author><author><name sortKey="Lilla, S" uniqKey="Lilla S">S Lilla</name></author><author><name sortKey="Martin Perez, R" uniqKey="Martin Perez R">R Martin-Perez</name></author><author><name sortKey="Mennerich, D" uniqKey="Mennerich D">D Mennerich</name></author><author><name sortKey="Boon, L" uniqKey="Boon L">L Boon</name></author><author><name sortKey="Hendrikx, S" uniqKey="Hendrikx S">S Hendrikx</name></author><author><name sortKey="Maddocks, Od" uniqKey="Maddocks O">OD Maddocks</name></author><author><name sortKey="Marx, C" uniqKey="Marx C">C Marx</name></author><author><name sortKey="Radhakrishnan, P" uniqKey="Radhakrishnan P">P Radhakrishnan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Maeda, H" uniqKey="Maeda H">H Maeda</name></author><author><name sortKey="Wu, J" uniqKey="Wu J">J Wu</name></author><author><name sortKey="Sawa, T" uniqKey="Sawa T">T Sawa</name></author><author><name sortKey="Matsumura, Y" uniqKey="Matsumura Y">Y Matsumura</name></author><author><name sortKey="Hori, K" uniqKey="Hori K">K Hori</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nelson, Da" uniqKey="Nelson D">DA Nelson</name></author><author><name sortKey="Tan, Tt" uniqKey="Tan T">TT Tan</name></author><author><name sortKey="Rabson, Ab" uniqKey="Rabson A">AB Rabson</name></author><author><name sortKey="Anderson, D" uniqKey="Anderson D">D Anderson</name></author><author><name sortKey="Degenhardt, K" uniqKey="Degenhardt K">K Degenhardt</name></author><author><name sortKey="White, E" uniqKey="White E">E White</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jain, Rk" uniqKey="Jain R">RK Jain</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Whatcott, Cj" uniqKey="Whatcott C">CJ Whatcott</name></author><author><name sortKey="Han, H" uniqKey="Han H">H Han</name></author><author><name sortKey="Von Hoff, Dd" uniqKey="Von Hoff D">DD Von Hoff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gaggioli, C" uniqKey="Gaggioli C">C Gaggioli</name></author><author><name sortKey="Hooper, S" uniqKey="Hooper S">S Hooper</name></author><author><name sortKey="Hidalgo Carcedo, C" uniqKey="Hidalgo Carcedo C">C Hidalgo-Carcedo</name></author><author><name sortKey="Grosse, R" uniqKey="Grosse R">R Grosse</name></author><author><name sortKey="Marshall, Jf" uniqKey="Marshall J">JF Marshall</name></author><author><name sortKey="Harrington, K" uniqKey="Harrington K">K Harrington</name></author><author><name sortKey="Sahai, E" uniqKey="Sahai E">E Sahai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thiery, Jp" uniqKey="Thiery J">JP Thiery</name></author><author><name sortKey="Acloque, H" uniqKey="Acloque H">H Acloque</name></author><author><name sortKey="Huang, Ry" uniqKey="Huang R">RY Huang</name></author><author><name sortKey="Nieto, Ma" uniqKey="Nieto M">MA Nieto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pastorek, J" uniqKey="Pastorek J">J Pastorek</name></author><author><name sortKey="Pastorekova, S" uniqKey="Pastorekova S">S Pastorekova</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pilon Thomas, S" uniqKey="Pilon Thomas S">S Pilon-Thomas</name></author><author><name sortKey="Kodumudi, Kn" uniqKey="Kodumudi K">KN Kodumudi</name></author><author><name sortKey="El Kenawi, Ae" uniqKey="El Kenawi A">AE El-Kenawi</name></author><author><name sortKey="Russell, S" uniqKey="Russell S">S Russell</name></author><author><name sortKey="Weber, Am" uniqKey="Weber A">AM Weber</name></author><author><name sortKey="Luddy, K" uniqKey="Luddy K">K Luddy</name></author><author><name sortKey="Damaghi, M" uniqKey="Damaghi M">M Damaghi</name></author><author><name sortKey="Wojtkowiak, Jw" uniqKey="Wojtkowiak J">JW Wojtkowiak</name></author><author><name sortKey="Mule, Jj" uniqKey="Mule J">JJ Mule</name></author><author><name sortKey="Ibrahim Hashim, A" uniqKey="Ibrahim Hashim A">A Ibrahim-Hashim</name></author><author><name sortKey="Gillies, Rj" uniqKey="Gillies R">RJ Gillies</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sgarbi, Gianluca" uniqKey="Sgarbi G">Gianluca Sgarbi</name></author><author><name sortKey="Gorini, Giulia" uniqKey="Gorini G">Giulia Gorini</name></author><author><name sortKey="Liuzzi, Francesca" uniqKey="Liuzzi F">Francesca Liuzzi</name></author><author><name sortKey="Solaini, Giancarlo" uniqKey="Solaini G">Giancarlo Solaini</name></author><author><name sortKey="Baracca, Alessandra" uniqKey="Baracca A">Alessandra Baracca</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhu, X" uniqKey="Zhu X">X Zhu</name></author><author><name sortKey="Zuo, L" uniqKey="Zuo L">L Zuo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guzy, Rd" uniqKey="Guzy R">RD Guzy</name></author><author><name sortKey="Hoyos, B" uniqKey="Hoyos B">B Hoyos</name></author><author><name sortKey="Robin, E" uniqKey="Robin E">E Robin</name></author><author><name sortKey="Chen, H" uniqKey="Chen H">H Chen</name></author><author><name sortKey="Liu, L" uniqKey="Liu L">L Liu</name></author><author><name sortKey="Mansfield, Kd" uniqKey="Mansfield K">KD Mansfield</name></author><author><name sortKey="Simon, Mc" uniqKey="Simon M">MC Simon</name></author><author><name sortKey="Hammerling, U" uniqKey="Hammerling U">U Hammerling</name></author><author><name sortKey="Schumacker, Pt" uniqKey="Schumacker P">PT Schumacker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nita, M" uniqKey="Nita M">M Nita</name></author><author><name sortKey="Grzybowski, A" uniqKey="Grzybowski A">A Grzybowski</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bridge, G" uniqKey="Bridge G">G Bridge</name></author><author><name sortKey="Rashid, S" uniqKey="Rashid S">S Rashid</name></author><author><name sortKey="Martin, Sa" uniqKey="Martin S">SA Martin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Syu, Jp" uniqKey="Syu J">JP Syu</name></author><author><name sortKey="Chi, Jt" uniqKey="Chi J">JT Chi</name></author><author><name sortKey="Kung, Hn" uniqKey="Kung H">HN Kung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shen, Y" uniqKey="Shen Y">Y Shen</name></author><author><name sortKey="Yang, J" uniqKey="Yang J">J Yang</name></author><author><name sortKey="Zhao, J" uniqKey="Zhao J">J Zhao</name></author><author><name sortKey="Xiao, C" uniqKey="Xiao C">C Xiao</name></author><author><name sortKey="Xu, C" uniqKey="Xu C">C Xu</name></author><author><name sortKey="Xiang, Y" uniqKey="Xiang Y">Y Xiang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Corzo, Ca" uniqKey="Corzo C">CA Corzo</name></author><author><name sortKey="Condamine, T" uniqKey="Condamine T">T Condamine</name></author><author><name sortKey="Lu, L" uniqKey="Lu L">L Lu</name></author><author><name sortKey="Cotter, Mj" uniqKey="Cotter M">MJ Cotter</name></author><author><name sortKey="Youn, Ji" uniqKey="Youn J">JI Youn</name></author><author><name sortKey="Cheng, P" uniqKey="Cheng P">P Cheng</name></author><author><name sortKey="Cho, Hi" uniqKey="Cho H">HI Cho</name></author><author><name sortKey="Celis, E" uniqKey="Celis E">E Celis</name></author><author><name sortKey="Quiceno, Dg" uniqKey="Quiceno D">DG Quiceno</name></author><author><name sortKey="Padhya, T" uniqKey="Padhya T">T Padhya</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mantovani, A" uniqKey="Mantovani A">A Mantovani</name></author><author><name sortKey="Sozzani, S" uniqKey="Sozzani S">S Sozzani</name></author><author><name sortKey="Locati, M" uniqKey="Locati M">M Locati</name></author><author><name sortKey="Allavena, P" uniqKey="Allavena P">P Allavena</name></author><author><name sortKey="Sica, A" uniqKey="Sica A">A Sica</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Noman, Mz" uniqKey="Noman M">MZ Noman</name></author><author><name sortKey="Desantis, G" uniqKey="Desantis G">G Desantis</name></author><author><name sortKey="Janji, B" uniqKey="Janji B">B Janji</name></author><author><name sortKey="Hasmim, M" uniqKey="Hasmim M">M Hasmim</name></author><author><name sortKey="Karray, S" uniqKey="Karray S">S Karray</name></author><author><name sortKey="Dessen, P" uniqKey="Dessen P">P Dessen</name></author><author><name sortKey="Bronte, V" uniqKey="Bronte V">V Bronte</name></author><author><name sortKey="Chouaib, S" uniqKey="Chouaib S">S Chouaib</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barsoum, Ib" uniqKey="Barsoum I">IB Barsoum</name></author><author><name sortKey="Smallwood, Ca" uniqKey="Smallwood C">CA Smallwood</name></author><author><name sortKey="Siemens, Dr" uniqKey="Siemens D">DR Siemens</name></author><author><name sortKey="Graham, Ch" uniqKey="Graham C">CH Graham</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Saggar, Jk" uniqKey="Saggar J">JK Saggar</name></author><author><name sortKey="Yu, M" uniqKey="Yu M">M Yu</name></author><author><name sortKey="Tan, Q" uniqKey="Tan Q">Q Tan</name></author><author><name sortKey="Tannock, If" uniqKey="Tannock I">IF Tannock</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, H" uniqKey="Li H">H Li</name></author><author><name sortKey="Rokavec, M" uniqKey="Rokavec M">M Rokavec</name></author><author><name sortKey="Jiang, L" uniqKey="Jiang L">L Jiang</name></author><author><name sortKey="Horst, D" uniqKey="Horst D">D Horst</name></author><author><name sortKey="Hermeking, H" uniqKey="Hermeking H">H Hermeking</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ueda, S" uniqKey="Ueda S">S Ueda</name></author><author><name sortKey="Saeki, T" uniqKey="Saeki T">T Saeki</name></author><author><name sortKey="Osaki, A" uniqKey="Osaki A">A Osaki</name></author><author><name sortKey="Yamane, T" uniqKey="Yamane T">T Yamane</name></author><author><name sortKey="Kuji, I" uniqKey="Kuji I">I Kuji</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, A" uniqKey="Chen A">A Chen</name></author><author><name sortKey="Sceneay, J" uniqKey="Sceneay J">J Sceneay</name></author><author><name sortKey="Godde, N" uniqKey="Godde N">N Godde</name></author><author><name sortKey="Kinwel, T" uniqKey="Kinwel T">T Kinwel</name></author><author><name sortKey="Ham, S" uniqKey="Ham S">S Ham</name></author><author><name sortKey="Thompson, Ew" uniqKey="Thompson E">EW Thompson</name></author><author><name sortKey="Humbert, Po" uniqKey="Humbert P">PO Humbert</name></author><author><name sortKey="Moller, A" uniqKey="Moller A">A Moller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, Steven H" uniqKey="Lin S">Steven H Lin</name></author><author><name sortKey="Koong, Albert C" uniqKey="Koong A">Albert C Koong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Unruh, A" uniqKey="Unruh A">A Unruh</name></author><author><name sortKey="Ressel, A" uniqKey="Ressel A">A Ressel</name></author><author><name sortKey="Mohamed, Hg" uniqKey="Mohamed H">HG Mohamed</name></author><author><name sortKey="Johnson, Rs" uniqKey="Johnson R">RS Johnson</name></author><author><name sortKey="Nadrowitz, R" uniqKey="Nadrowitz R">R Nadrowitz</name></author><author><name sortKey="Richter, E" uniqKey="Richter E">E Richter</name></author><author><name sortKey="Katschinski, Dm" uniqKey="Katschinski D">DM Katschinski</name></author><author><name sortKey="Wenger, Rh" uniqKey="Wenger R">RH Wenger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Daponte, A" uniqKey="Daponte A">A Daponte</name></author><author><name sortKey="Ioannou, M" uniqKey="Ioannou M">M Ioannou</name></author><author><name sortKey="Mylonis, I" uniqKey="Mylonis I">I Mylonis</name></author><author><name sortKey="Simos, G" uniqKey="Simos G">G Simos</name></author><author><name sortKey="Minas, M" uniqKey="Minas M">M Minas</name></author><author><name sortKey="Messinis, Ie" uniqKey="Messinis I">IE Messinis</name></author><author><name sortKey="Koukoulis, G" uniqKey="Koukoulis G">G Koukoulis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mayer, A" uniqKey="Mayer A">A Mayer</name></author><author><name sortKey="Hockel, M" uniqKey="Hockel M">M Hockel</name></author><author><name sortKey="Wree, A" uniqKey="Wree A">A Wree</name></author><author><name sortKey="Leo, C" uniqKey="Leo C">C Leo</name></author><author><name sortKey="Horn, Lc" uniqKey="Horn L">LC Horn</name></author><author><name sortKey="Vaupel, P" uniqKey="Vaupel P">P Vaupel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Simiantonaki, N" uniqKey="Simiantonaki N">N Simiantonaki</name></author><author><name sortKey="Taxeidis, M" uniqKey="Taxeidis M">M Taxeidis</name></author><author><name sortKey="Jayasinghe, C" uniqKey="Jayasinghe C">C Jayasinghe</name></author><author><name sortKey="Kurzik Dumke, U" uniqKey="Kurzik Dumke U">U Kurzik-Dumke</name></author><author><name sortKey="Kirkpatrick, Cj" uniqKey="Kirkpatrick C">CJ Kirkpatrick</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sun, Hc" uniqKey="Sun H">HC Sun</name></author><author><name sortKey="Qiu, Zj" uniqKey="Qiu Z">ZJ Qiu</name></author><author><name sortKey="Liu, J" uniqKey="Liu J">J Liu</name></author><author><name sortKey="Sun, J" uniqKey="Sun J">J Sun</name></author><author><name sortKey="Jiang, T" uniqKey="Jiang T">T Jiang</name></author><author><name sortKey="Huang, Kj" uniqKey="Huang K">KJ Huang</name></author><author><name sortKey="Yao, M" uniqKey="Yao M">M Yao</name></author><author><name sortKey="Huang, C" uniqKey="Huang C">C Huang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, Jj" uniqKey="Zhang J">JJ Zhang</name></author><author><name sortKey="Wu, Hs" uniqKey="Wu H">HS Wu</name></author><author><name sortKey="Wang, L" uniqKey="Wang L">L Wang</name></author><author><name sortKey="Tian, Y" uniqKey="Tian Y">Y Tian</name></author><author><name sortKey="Zhang, Jh" uniqKey="Zhang J">JH Zhang</name></author><author><name sortKey="Wu, Hl" uniqKey="Wu H">HL Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoffmann, Ac" uniqKey="Hoffmann A">AC Hoffmann</name></author><author><name sortKey="Mori, R" uniqKey="Mori R">R Mori</name></author><author><name sortKey="Vallbohmer, D" uniqKey="Vallbohmer D">D Vallbohmer</name></author><author><name sortKey="Brabender, J" uniqKey="Brabender J">J Brabender</name></author><author><name sortKey="Klein, E" uniqKey="Klein E">E Klein</name></author><author><name sortKey="Drebber, U" uniqKey="Drebber U">U Drebber</name></author><author><name sortKey="Baldus, Se" uniqKey="Baldus S">SE Baldus</name></author><author><name sortKey="Cooc, J" uniqKey="Cooc J">J Cooc</name></author><author><name sortKey="Azuma, M" uniqKey="Azuma M">M Azuma</name></author><author><name sortKey="Metzger, R" uniqKey="Metzger R">R Metzger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhitomirsky, B" uniqKey="Zhitomirsky B">B Zhitomirsky</name></author><author><name sortKey="Assaraf, Yg" uniqKey="Assaraf Y">YG Assaraf</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zub, Ka" uniqKey="Zub K">KA Zub</name></author><author><name sortKey="Sousa, Mm" uniqKey="Sousa M">MM Sousa</name></author><author><name sortKey="Sarno, A" uniqKey="Sarno A">A Sarno</name></author><author><name sortKey="Sharma, A" uniqKey="Sharma A">A Sharma</name></author><author><name sortKey="Demirovic, A" uniqKey="Demirovic A">A Demirovic</name></author><author><name sortKey="Rao, S" uniqKey="Rao S">S Rao</name></author><author><name sortKey="Young, C" uniqKey="Young C">C Young</name></author><author><name sortKey="Aas, Pa" uniqKey="Aas P">PA Aas</name></author><author><name sortKey="Ericsson, I" uniqKey="Ericsson I">I Ericsson</name></author><author><name sortKey="Sundan, A" uniqKey="Sundan A">A Sundan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Y" uniqKey="Li Y">Y Li</name></author><author><name sortKey="Xiang, J" uniqKey="Xiang J">J Xiang</name></author><author><name sortKey="Zhang, Ss" uniqKey="Zhang S">SS Zhang</name></author><author><name sortKey="Liu, Bz" uniqKey="Liu B">BZ Liu</name></author><author><name sortKey="Gong, F" uniqKey="Gong F">F Gong</name></author><author><name sortKey="Peng, Mq" uniqKey="Peng M">MQ Peng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Triner, D" uniqKey="Triner D">D Triner</name></author><author><name sortKey="Shah, Ym" uniqKey="Shah Y">YM Shah</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Silva, Vl" uniqKey="Silva V">VL Silva</name></author><author><name sortKey="Al Jamal, Wt" uniqKey="Al Jamal W">WT Al-Jamal</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gillet, J" uniqKey="Gillet J">J GILLET</name></author><author><name sortKey="Efferth, T" uniqKey="Efferth T">T EFFERTH</name></author><author><name sortKey="Remacle, J" uniqKey="Remacle J">J REMACLE</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dean, M" uniqKey="Dean M">M Dean</name></author><author><name sortKey="Annilo, T" uniqKey="Annilo T">T Annilo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, J" uniqKey="Chen J">J Chen</name></author><author><name sortKey="Ding, Z" uniqKey="Ding Z">Z Ding</name></author><author><name sortKey="Peng, Y" uniqKey="Peng Y">Y Peng</name></author><author><name sortKey="Pan, F" uniqKey="Pan F">F Pan</name></author><author><name sortKey="Li, J" uniqKey="Li J">J Li</name></author><author><name sortKey="Zou, L" uniqKey="Zou L">L Zou</name></author><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y Zhang</name></author><author><name sortKey="Liang, H" uniqKey="Liang H">H Liang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Maddika, S" uniqKey="Maddika S">S Maddika</name></author><author><name sortKey="Ande, Sr" uniqKey="Ande S">SR Ande</name></author><author><name sortKey="Panigrahi, S" uniqKey="Panigrahi S">S Panigrahi</name></author><author><name sortKey="Paranjothy, T" uniqKey="Paranjothy T">T Paranjothy</name></author><author><name sortKey="Weglarczyk, K" uniqKey="Weglarczyk K">K Weglarczyk</name></author><author><name sortKey="Zuse, A" uniqKey="Zuse A">A Zuse</name></author><author><name sortKey="Eshraghi, M" uniqKey="Eshraghi M">M Eshraghi</name></author><author><name sortKey="Manda, Kd" uniqKey="Manda K">KD Manda</name></author><author><name sortKey="Wiechec, E" uniqKey="Wiechec E">E Wiechec</name></author><author><name sortKey="Los, M" uniqKey="Los M">M Los</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Enari, M" uniqKey="Enari M">M Enari</name></author><author><name sortKey="Sakahira, H" uniqKey="Sakahira H">H Sakahira</name></author><author><name sortKey="Yokoyama, H" uniqKey="Yokoyama H">H Yokoyama</name></author><author><name sortKey="Okawa, K" uniqKey="Okawa K">K Okawa</name></author><author><name sortKey="Iwamatsu, A" uniqKey="Iwamatsu A">A Iwamatsu</name></author><author><name sortKey="Nagata, S" uniqKey="Nagata S">S Nagata</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mow, Bmf" uniqKey="Mow B">BMF Mow</name></author><author><name sortKey="Blajeski, Al" uniqKey="Blajeski A">AL Blajeski</name></author><author><name sortKey="Chandra, J" uniqKey="Chandra J">J Chandra</name></author><author><name sortKey="Kaufmann, Sh" uniqKey="Kaufmann S">SH Kaufmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Siegel, Rm" uniqKey="Siegel R">RM Siegel</name></author><author><name sortKey="Martin, Da" uniqKey="Martin D">DA Martin</name></author><author><name sortKey="Zheng, L" uniqKey="Zheng L">L Zheng</name></author><author><name sortKey="Ng, Sy" uniqKey="Ng S">SY Ng</name></author><author><name sortKey="Bertin, J" uniqKey="Bertin J">J Bertin</name></author><author><name sortKey="Cohen, J" uniqKey="Cohen J">J Cohen</name></author><author><name sortKey="Lenardo, Mj" uniqKey="Lenardo M">MJ Lenardo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kroemer, G" uniqKey="Kroemer G">G Kroemer</name></author><author><name sortKey="Reed, Jc" uniqKey="Reed J">JC Reed</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Erler, Jt" uniqKey="Erler J">JT Erler</name></author><author><name sortKey="Cawthorne, Cj" uniqKey="Cawthorne C">CJ Cawthorne</name></author><author><name sortKey="Williams, Kj" uniqKey="Williams K">KJ Williams</name></author><author><name sortKey="Koritzinsky, M" uniqKey="Koritzinsky M">M Koritzinsky</name></author><author><name sortKey="Wouters, Bg" uniqKey="Wouters B">BG Wouters</name></author><author><name sortKey="Wilson, C" uniqKey="Wilson C">C Wilson</name></author><author><name sortKey="Miller, C" uniqKey="Miller C">C Miller</name></author><author><name sortKey="Demonacos, C" uniqKey="Demonacos C">C Demonacos</name></author><author><name sortKey="Stratford, Ij" uniqKey="Stratford I">IJ Stratford</name></author><author><name sortKey="Dive, C" uniqKey="Dive C">C Dive</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sakamoto, H" uniqKey="Sakamoto H">H Sakamoto</name></author><author><name sortKey="Mashima, T" uniqKey="Mashima T">T Mashima</name></author><author><name sortKey="Kizaki, A" uniqKey="Kizaki A">A Kizaki</name></author><author><name sortKey="Dan, S" uniqKey="Dan S">S Dan</name></author><author><name sortKey="Hashimoto, Y" uniqKey="Hashimoto Y">Y Hashimoto</name></author><author><name sortKey="Naito, M" uniqKey="Naito M">M Naito</name></author><author><name sortKey="Tsuruo, T" uniqKey="Tsuruo T">T Tsuruo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thornalley, Pj" uniqKey="Thornalley P">PJ Thornalley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sakamoto, H" uniqKey="Sakamoto H">H Sakamoto</name></author><author><name sortKey="Mashima, T" uniqKey="Mashima T">T Mashima</name></author><author><name sortKey="Sato, S" uniqKey="Sato S">S Sato</name></author><author><name sortKey="Hashimoto, Y" uniqKey="Hashimoto Y">Y Hashimoto</name></author><author><name sortKey="Yamori, T" uniqKey="Yamori T">T Yamori</name></author><author><name sortKey="Tsuruo, T" uniqKey="Tsuruo T">T Tsuruo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rohwer, N" uniqKey="Rohwer N">N Rohwer</name></author><author><name sortKey="Dame, C" uniqKey="Dame C">C Dame</name></author><author><name sortKey="Haugstetter, A" uniqKey="Haugstetter A">A Haugstetter</name></author><author><name sortKey="Wiedenmann, B" uniqKey="Wiedenmann B">B Wiedenmann</name></author><author><name sortKey="Detjen, K" uniqKey="Detjen K">K Detjen</name></author><author><name sortKey="Schmitt, Ca" uniqKey="Schmitt C">CA Schmitt</name></author><author><name sortKey="Cramer, T" uniqKey="Cramer T">T Cramer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Achison, M" uniqKey="Achison M">M Achison</name></author><author><name sortKey="Hupp, Tr" uniqKey="Hupp T">TR Hupp</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mizushima, N" uniqKey="Mizushima N">N Mizushima</name></author><author><name sortKey="Levine, B" uniqKey="Levine B">B Levine</name></author><author><name sortKey="Cuervo, Am" uniqKey="Cuervo A">AM Cuervo</name></author><author><name sortKey="Klionsky, Dj" uniqKey="Klionsky D">DJ Klionsky</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Li, C" uniqKey="Li C">C Li</name></author><author><name sortKey="Liao, W" uniqKey="Liao W">W Liao</name></author><author><name sortKey="Wu, M" uniqKey="Wu M">M Wu</name></author><author><name sortKey="Chu, P" uniqKey="Chu P">P Chu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, S" uniqKey="Chen S">S Chen</name></author><author><name sortKey="Rehman, Sk" uniqKey="Rehman S">SK Rehman</name></author><author><name sortKey="Zhang, W" uniqKey="Zhang W">W Zhang</name></author><author><name sortKey="Wen, A" uniqKey="Wen A">A Wen</name></author><author><name sortKey="Yao, L" uniqKey="Yao L">L Yao</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, J" uniqKey="Kim J">J Kim</name></author><author><name sortKey="Kundu, M" uniqKey="Kundu M">M Kundu</name></author><author><name sortKey="Viollet, B" uniqKey="Viollet B">B Viollet</name></author><author><name sortKey="Guan, Kl" uniqKey="Guan K">KL Guan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, X" uniqKey="Liu X">X Liu</name></author><author><name sortKey="Su, Y" uniqKey="Su Y">Y Su</name></author><author><name sortKey="Zhu, H" uniqKey="Zhu H">H Zhu</name></author><author><name sortKey="Cao, J" uniqKey="Cao J">J Cao</name></author><author><name sortKey="Ding, W" uniqKey="Ding W">W Ding</name></author><author><name sortKey="Zhao, Y" uniqKey="Zhao Y">Y Zhao</name></author><author><name sortKey="He, Q" uniqKey="He Q">Q He</name></author><author><name sortKey="Yang, B" uniqKey="Yang B">B Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, M" uniqKey="Yang M">M Yang</name></author><author><name sortKey="Zeng, P" uniqKey="Zeng P">P Zeng</name></author><author><name sortKey="Kang, R" uniqKey="Kang R">R Kang</name></author><author><name sortKey="Yu, Y" uniqKey="Yu Y">Y Yu</name></author><author><name sortKey="Yang, L" uniqKey="Yang L">L Yang</name></author><author><name sortKey="Tang, D" uniqKey="Tang D">D Tang</name></author><author><name sortKey="Cao, L" uniqKey="Cao L">L Cao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pan, B" uniqKey="Pan B">B Pan</name></author><author><name sortKey="Chen, D" uniqKey="Chen D">D Chen</name></author><author><name sortKey="Huang, J" uniqKey="Huang J">J Huang</name></author><author><name sortKey="Wang, R" uniqKey="Wang R">R Wang</name></author><author><name sortKey="Feng, B" uniqKey="Feng B">B Feng</name></author><author><name sortKey="Song, H" uniqKey="Song H">H Song</name></author><author><name sortKey="Chen, L" uniqKey="Chen L">L Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fan, T" uniqKey="Fan T">T Fan</name></author><author><name sortKey="Zhang, C" uniqKey="Zhang C">C Zhang</name></author><author><name sortKey="Zong, M" uniqKey="Zong M">M Zong</name></author><author><name sortKey="Zhao, Q" uniqKey="Zhao Q">Q Zhao</name></author><author><name sortKey="Yang, X" uniqKey="Yang X">X Yang</name></author><author><name sortKey="Hao, C" uniqKey="Hao C">C Hao</name></author><author><name sortKey="Zhang, H" uniqKey="Zhang H">H Zhang</name></author><author><name sortKey="Yu, S" uniqKey="Yu S">S Yu</name></author><author><name sortKey="Guo, J" uniqKey="Guo J">J Guo</name></author><author><name sortKey="Gong, R" uniqKey="Gong R">R Gong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="An, Y" uniqKey="An Y">Y An</name></author><author><name sortKey="Zhang, Z" uniqKey="Zhang Z">Z Zhang</name></author><author><name sortKey="Shang, Y" uniqKey="Shang Y">Y Shang</name></author><author><name sortKey="Jiang, X" uniqKey="Jiang X">X Jiang</name></author><author><name sortKey="Dong, J" uniqKey="Dong J">J Dong</name></author><author><name sortKey="Yu, P" uniqKey="Yu P">P Yu</name></author><author><name sortKey="Nie, Y" uniqKey="Nie Y">Y Nie</name></author><author><name sortKey="Zhao, Q" uniqKey="Zhao Q">Q Zhao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="O Donovan, Tr" uniqKey="O Donovan T">TR O'Donovan</name></author><author><name sortKey="O Sullivan, Gc" uniqKey="O Sullivan G">GC O'Sullivan</name></author><author><name sortKey="Mckenna, Sl" uniqKey="Mckenna S">SL McKenna</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, Wm" uniqKey="Lin W">WM Lin</name></author><author><name sortKey="Li, Zg" uniqKey="Li Z">ZG Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, Hm" uniqKey="Wu H">HM Wu</name></author><author><name sortKey="Shao, Lj" uniqKey="Shao L">LJ Shao</name></author><author><name sortKey="Jiang, Zf" uniqKey="Jiang Z">ZF Jiang</name></author><author><name sortKey="Liu, Ry" uniqKey="Liu R">RY Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bristow, Rg" uniqKey="Bristow R">RG Bristow</name></author><author><name sortKey="Hill, Rp" uniqKey="Hill R">RP Hill</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Olcina, M" uniqKey="Olcina M">M Olcina</name></author><author><name sortKey="Lecane, Ps" uniqKey="Lecane P">PS Lecane</name></author><author><name sortKey="Hammond, Em" uniqKey="Hammond E">EM Hammond</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Smith, J" uniqKey="Smith J">J Smith</name></author><author><name sortKey="Tho, Lm" uniqKey="Tho L">LM Tho</name></author><author><name sortKey="Xu, N" uniqKey="Xu N">N Xu</name></author><author><name sortKey="Gillespie, Da" uniqKey="Gillespie D">DA Gillespie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wirthner, R" uniqKey="Wirthner R">R Wirthner</name></author><author><name sortKey="Wrann, S" uniqKey="Wrann S">S Wrann</name></author><author><name sortKey="Balamurugan, K" uniqKey="Balamurugan K">K Balamurugan</name></author><author><name sortKey="Wenger, Rh" uniqKey="Wenger R">RH Wenger</name></author><author><name sortKey="Stiehl, Dp" uniqKey="Stiehl D">DP Stiehl</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Semenza, Gl" uniqKey="Semenza G">GL Semenza</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xu, Rh" uniqKey="Xu R">RH Xu</name></author><author><name sortKey="Pelicano, H" uniqKey="Pelicano H">H Pelicano</name></author><author><name sortKey="Zhou, Y" uniqKey="Zhou Y">Y Zhou</name></author><author><name sortKey="Carew, Js" uniqKey="Carew J">JS Carew</name></author><author><name sortKey="Feng, L" uniqKey="Feng L">L Feng</name></author><author><name sortKey="Bhalla, Kn" uniqKey="Bhalla K">KN Bhalla</name></author><author><name sortKey="Keating, Mj" uniqKey="Keating M">MJ Keating</name></author><author><name sortKey="Huang, P" uniqKey="Huang P">P Huang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tosatto, A" uniqKey="Tosatto A">A Tosatto</name></author><author><name sortKey="Sommaggio, R" uniqKey="Sommaggio R">R Sommaggio</name></author><author><name sortKey="Kummerow, C" uniqKey="Kummerow C">C Kummerow</name></author><author><name sortKey="Bentham, Rb" uniqKey="Bentham R">RB Bentham</name></author><author><name sortKey="Blacker, Ts" uniqKey="Blacker T">TS Blacker</name></author><author><name sortKey="Berecz, T" uniqKey="Berecz T">T Berecz</name></author><author><name sortKey="Duchen, Mr" uniqKey="Duchen M">MR Duchen</name></author><author><name sortKey="Rosato, A" uniqKey="Rosato A">A Rosato</name></author><author><name sortKey="Bogeski, I" uniqKey="Bogeski I">I Bogeski</name></author><author><name sortKey="Szabadkai, G" uniqKey="Szabadkai G">G Szabadkai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fukuda, R" uniqKey="Fukuda R">R Fukuda</name></author><author><name sortKey="Zhang, H" uniqKey="Zhang H">H Zhang</name></author><author><name sortKey="Kim, Jw" uniqKey="Kim J">JW Kim</name></author><author><name sortKey="Shimoda, L" uniqKey="Shimoda L">L Shimoda</name></author><author><name sortKey="Dang, Cv" uniqKey="Dang C">CV Dang</name></author><author><name sortKey="Semenza, Gl" uniqKey="Semenza G">GL Semenza</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Papandreou, I" uniqKey="Papandreou I">I Papandreou</name></author><author><name sortKey="Cairns, Ra" uniqKey="Cairns R">RA Cairns</name></author><author><name sortKey="Fontana, L" uniqKey="Fontana L">L Fontana</name></author><author><name sortKey="Lim, Al" uniqKey="Lim A">AL Lim</name></author><author><name sortKey="Denko, Nc" uniqKey="Denko N">NC Denko</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zeller, Ki" uniqKey="Zeller K">KI Zeller</name></author><author><name sortKey="Zhao, X" uniqKey="Zhao X">X Zhao</name></author><author><name sortKey="Charlie, Whl" uniqKey="Charlie W">WHL Charlie</name></author><author><name sortKey="Chiu, Kp" uniqKey="Chiu K">KP Chiu</name></author><author><name sortKey="Yao, F" uniqKey="Yao F">F Yao</name></author><author><name sortKey="Yustein, Jt" uniqKey="Yustein J">JT Yustein</name></author><author><name sortKey="Ooi, Hs" uniqKey="Ooi H">HS Ooi</name></author><author><name sortKey="Orlov, Yl" uniqKey="Orlov Y">YL Orlov</name></author><author><name sortKey="Shahab, A" uniqKey="Shahab A">A Shahab</name></author><author><name sortKey="Yong, Hc" uniqKey="Yong H">HC Yong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Maranchie, Jk" uniqKey="Maranchie J">JK Maranchie</name></author><author><name sortKey="Vasselli, Jr" uniqKey="Vasselli J">JR Vasselli</name></author><author><name sortKey="Riss, J" uniqKey="Riss J">J Riss</name></author><author><name sortKey="Bonifacino, Js" uniqKey="Bonifacino J">JS Bonifacino</name></author><author><name sortKey="Linehan, Wm" uniqKey="Linehan W">WM Linehan</name></author><author><name sortKey="Klausner, Rd" uniqKey="Klausner R">RD Klausner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kandoth, C" uniqKey="Kandoth C">C Kandoth</name></author><author><name sortKey="Mclellan, Md" uniqKey="Mclellan M">MD McLellan</name></author><author><name sortKey="Vandin, F" uniqKey="Vandin F">F Vandin</name></author><author><name sortKey="Ye, K" uniqKey="Ye K">K Ye</name></author><author><name sortKey="Niu, B" uniqKey="Niu B">B Niu</name></author><author><name sortKey="Lu, C" uniqKey="Lu C">C Lu</name></author><author><name sortKey="Xie, M" uniqKey="Xie M">M Xie</name></author><author><name sortKey="Zhang, Q" uniqKey="Zhang Q">Q Zhang</name></author><author><name sortKey="Mcmichael, Jf" uniqKey="Mcmichael J">JF McMichael</name></author><author><name sortKey="Wyczalkowski, Ma" uniqKey="Wyczalkowski M">MA Wyczalkowski</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Soussi, T" uniqKey="Soussi T">T Soussi</name></author><author><name sortKey="Wiman, Kg" uniqKey="Wiman K">KG Wiman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sermeus, A" uniqKey="Sermeus A">A Sermeus</name></author><author><name sortKey="Michiels, C" uniqKey="Michiels C">C Michiels</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Koshikawa, N" uniqKey="Koshikawa N">N Koshikawa</name></author><author><name sortKey="Maejima, C" uniqKey="Maejima C">C Maejima</name></author><author><name sortKey="Miyazaki, K" uniqKey="Miyazaki K">K Miyazaki</name></author><author><name sortKey="Nakagawara, A" uniqKey="Nakagawara A">A Nakagawara</name></author><author><name sortKey="Takenaga, K" uniqKey="Takenaga K">K Takenaga</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, Cy" uniqKey="Kim C">CY Kim</name></author><author><name sortKey="Tsai, Mh" uniqKey="Tsai M">MH Tsai</name></author><author><name sortKey="Osmanian, C" uniqKey="Osmanian C">C Osmanian</name></author><author><name sortKey="Graeber, Tg" uniqKey="Graeber T">TG Graeber</name></author><author><name sortKey="Lee, Je" uniqKey="Lee J">JE Lee</name></author><author><name sortKey="Giffard, Rg" uniqKey="Giffard R">RG Giffard</name></author><author><name sortKey="Dipaolo, Ja" uniqKey="Dipaolo J">JA DiPaolo</name></author><author><name sortKey="Peehl, Dm" uniqKey="Peehl D">DM Peehl</name></author><author><name sortKey="Giaccia, Aj" uniqKey="Giaccia A">AJ Giaccia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wohlkoenig, C" uniqKey="Wohlkoenig C">C Wohlkoenig</name></author><author><name sortKey="Leithner, K" uniqKey="Leithner K">K Leithner</name></author><author><name sortKey="Deutsch, A" uniqKey="Deutsch A">A Deutsch</name></author><author><name sortKey="Hrzenjak, A" uniqKey="Hrzenjak 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Denny</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hunter, Fw" uniqKey="Hunter F">FW Hunter</name></author><author><name sortKey="Young, Rj" uniqKey="Young R">RJ Young</name></author><author><name sortKey="Shalev, Z" uniqKey="Shalev Z">Z Shalev</name></author><author><name sortKey="Vellanki, Rn" uniqKey="Vellanki R">RN Vellanki</name></author><author><name sortKey="Wang, J" uniqKey="Wang J">J Wang</name></author><author><name sortKey="Gu, Y" uniqKey="Gu Y">Y Gu</name></author><author><name sortKey="Joshi, N" uniqKey="Joshi N">N Joshi</name></author><author><name sortKey="Sreebhavan, S" uniqKey="Sreebhavan S">S Sreebhavan</name></author><author><name sortKey="Weinreb, I" uniqKey="Weinreb I">I Weinreb</name></author><author><name sortKey="Goldstein, Dp" uniqKey="Goldstein D">DP Goldstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Phillips, Rm" uniqKey="Phillips R">RM Phillips</name></author><author><name sortKey="Hendriks, Hr" uniqKey="Hendriks H">HR Hendriks</name></author><author><name sortKey="Peters, Gj" uniqKey="Peters G">GJ Peters</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shukla, Sk" uniqKey="Shukla S">SK Shukla</name></author><author><name sortKey="Purohit, V" uniqKey="Purohit V">V Purohit</name></author><author><name sortKey="Mehla, K" uniqKey="Mehla K">K Mehla</name></author><author><name sortKey="Gunda, V" uniqKey="Gunda V">V Gunda</name></author><author><name sortKey="Chaika, Nv" uniqKey="Chaika N">NV Chaika</name></author><author><name sortKey="Vernucci, E" uniqKey="Vernucci E">E Vernucci</name></author><author><name sortKey="King, Rj" uniqKey="King R">RJ King</name></author><author><name sortKey="Abrego, J" uniqKey="Abrego J">J Abrego</name></author><author><name sortKey="Goode, Gd" uniqKey="Goode G">GD Goode</name></author><author><name sortKey="Dasgupta, A" uniqKey="Dasgupta A">A Dasgupta</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xiong, G" uniqKey="Xiong G">G Xiong</name></author><author><name sortKey="Stewart, Rl" uniqKey="Stewart R">RL Stewart</name></author><author><name sortKey="Chen, J" uniqKey="Chen J">J Chen</name></author><author><name sortKey="Gao, T" uniqKey="Gao T">T Gao</name></author><author><name sortKey="Scott, Tl" uniqKey="Scott T">TL Scott</name></author><author><name sortKey="Samayoa, Lm" uniqKey="Samayoa L">LM Samayoa</name></author><author><name sortKey="O Connor, K" uniqKey="O Connor K">K O'Connor</name></author><author><name sortKey="Lane, An" uniqKey="Lane A">AN Lane</name></author><author><name sortKey="Xu, R" uniqKey="Xu R">R Xu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cui, Xy" uniqKey="Cui X">XY Cui</name></author><author><name sortKey="Tinholt, M" uniqKey="Tinholt M">M Tinholt</name></author><author><name sortKey="Stavik, B" uniqKey="Stavik B">B Stavik</name></author><author><name sortKey="Dahm, Ae" uniqKey="Dahm A">AE Dahm</name></author><author><name sortKey="Kanse, S" uniqKey="Kanse S">S Kanse</name></author><author><name sortKey="Jin, Y" uniqKey="Jin Y">Y Jin</name></author><author><name sortKey="Seidl, S" uniqKey="Seidl S">S Seidl</name></author><author><name sortKey="Sahlberg, Kk" uniqKey="Sahlberg K">KK Sahlberg</name></author><author><name sortKey="Iversen, N" uniqKey="Iversen N">N Iversen</name></author><author><name sortKey="Skretting, G" uniqKey="Skretting G">G Skretting</name></author><author><name sortKey="Sandset, Pm" uniqKey="Sandset P">PM Sandset</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kozlova, N" uniqKey="Kozlova N">N Kozlova</name></author><author><name sortKey="Wottawa, M" uniqKey="Wottawa M">M Wottawa</name></author><author><name sortKey="Katschinski, Dm" uniqKey="Katschinski D">DM Katschinski</name></author><author><name sortKey="Kristiansen, G" uniqKey="Kristiansen G">G Kristiansen</name></author><author><name sortKey="Kietzmann, T" uniqKey="Kietzmann T">T Kietzmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Federici, C" uniqKey="Federici C">C Federici</name></author><author><name sortKey="Petrucci, F" uniqKey="Petrucci F">F Petrucci</name></author><author><name sortKey="Caimi, S" uniqKey="Caimi S">S Caimi</name></author><author><name sortKey="Cesolini, A" uniqKey="Cesolini A">A Cesolini</name></author><author><name sortKey="Logozzi, M" uniqKey="Logozzi M">M Logozzi</name></author><author><name sortKey="Borghi, M" uniqKey="Borghi M">M Borghi</name></author><author><name sortKey="D Ilio, S" uniqKey="D Ilio S">S D'Ilio</name></author><author><name sortKey="Lugini, L" uniqKey="Lugini L">L Lugini</name></author><author><name sortKey="Violante, N" uniqKey="Violante N">N Violante</name></author><author><name sortKey="Azzarito, T" uniqKey="Azzarito T">T Azzarito</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, Yy" uniqKey="Lee Y">YY Lee</name></author><author><name sortKey="Jeon, Hk" uniqKey="Jeon H">HK Jeon</name></author><author><name sortKey="Hong, Je" uniqKey="Hong J">JE Hong</name></author><author><name sortKey="Cho, Yj" uniqKey="Cho Y">YJ Cho</name></author><author><name sortKey="Ryu, Jy" uniqKey="Ryu J">JY Ryu</name></author><author><name sortKey="Choi, Jj" uniqKey="Choi J">JJ Choi</name></author><author><name sortKey="Lee, Sh" uniqKey="Lee S">SH Lee</name></author><author><name sortKey="Yoon, G" uniqKey="Yoon G">G Yoon</name></author><author><name sortKey="Kim, Wy" uniqKey="Kim W">WY Kim</name></author><author><name sortKey="Do, Ig" uniqKey="Do I">IG Do</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Jing, Xinming" sort="Jing, Xinming" uniqKey="Jing X" first="Xinming" last="Jing">Xinming Jing</name></noRegion><name sortKey="Jing, Xinming" sort="Jing, Xinming" uniqKey="Jing X" first="Xinming" last="Jing">Xinming Jing</name><name sortKey="Shao, Chuchu" sort="Shao, Chuchu" uniqKey="Shao C" first="Chuchu" last="Shao">Chuchu Shao</name><name sortKey="Shao, Chuchu" sort="Shao, Chuchu" uniqKey="Shao C" first="Chuchu" last="Shao">Chuchu Shao</name><name sortKey="Shen, Hua" sort="Shen, Hua" uniqKey="Shen H" first="Hua" last="Shen">Hua Shen</name><name sortKey="Shen, Hua" sort="Shen, Hua" uniqKey="Shen H" first="Hua" last="Shen">Hua Shen</name><name sortKey="Shu, Yongqian" sort="Shu, Yongqian" uniqKey="Shu Y" first="Yongqian" last="Shu">Yongqian Shu</name><name sortKey="Shu, Yongqian" sort="Shu, Yongqian" uniqKey="Shu Y" first="Yongqian" last="Shu">Yongqian Shu</name><name sortKey="Wei, Ke" sort="Wei, Ke" uniqKey="Wei K" first="Ke" last="Wei">Ke Wei</name><name sortKey="Xie, Mengyan" sort="Xie, Mengyan" uniqKey="Xie M" first="Mengyan" last="Xie">Mengyan Xie</name><name sortKey="Xie, Mengyan" sort="Xie, Mengyan" uniqKey="Xie M" first="Mengyan" last="Xie">Mengyan Xie</name><name sortKey="Yang, Fengming" sort="Yang, Fengming" uniqKey="Yang F" first="Fengming" last="Yang">Fengming Yang</name><name sortKey="Yang, Fengming" sort="Yang, Fengming" uniqKey="Yang F" first="Fengming" last="Yang">Fengming Yang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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